HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Pyridinylboronic acid → (S)-1-fluoro-7-(5-(prop-1-ynyl)pyridin-3-yl)-3-(pyridin-3-yl)-5'H-spiro[chromeno[2,3-c]pyridine-5,4'-oxazol]-2'-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Pyridinylboronic acid | HCID 2734378 | — |
| Edukt | 5-(1-Propynyl)pyridine-3-boronic Acid (contains varying amounts of Anhydride) | HCID 57416482 | — |
| Edukt | (S)-7-bromo-3-chloro-1-fluoro-5'H-spiro[chromeno[2,3-c]pyridine-5,4' oxazol]-2'-amine | HCID 58466258 | — |
| Produkt | (S)-1-fluoro-7-(5-(prop-1-ynyl)pyridin-3-yl)-3-(pyridin-3-yl)-5'H-spiro[chromeno[2,3-c]pyridine-5,4'-oxazol]-2'-amine | HCID 58466193 | — |
Reaktionsschritte
The titled compound was synthesized by steps analogous to those described in method A1 above, but using (S)-7-bromo-3-chloro-1-fluoro-5′H-spiro[chromeno[2,3-c]pyridine-5,4′-oxazol]-2′-amine (prepared as described in Method BB33), pyridin-3-ylboronic acid and 5-(prop-1-ynyl)pyridin-3-ylboronic acid
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08883782B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-907b1d7cb5994c73b9ce94ac0d205141 |
| Quellennotiz | uspto-grants-2014_11 |