HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(2R)-1-Chloro-3-[[3-fluoro-4-(4-morpholinyl)phenyl]amino]-2-propanol → (R)-2-(3-((3-Fluoro-4-morpholinophenyl)amino)-2-hydroxypropyl)isoindoline-1,3-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (2R)-1-Chloro-3-[[3-fluoro-4-(4-morpholinyl)phenyl]amino]-2-propanol | HCID 16655948 | — |
| Edukt | Phthalimide potassium salt | HCID 24194345 | — |
| Produkt | (R)-2-(3-((3-Fluoro-4-morpholinophenyl)amino)-2-hydroxypropyl)isoindoline-1,3-dione | HCID 16655949 | — |
Reaktionsschritte
N-[3-Chloro-2-(R)-hydroxypropyl]-3-fluoro-4-morpholinyl aniline is reacted with potassium phthalimide to provide N-[3-pthalimido-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholinyl)aniline (Formula IV, R1═R3 is H; X is O; one R2 is H and the other R2 is F; and n is 1).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07429661B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-382f7809b6244d34a6777587c402b684 |
| Quellennotiz | uspto-grants-2008_09 |