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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 337736Erstellt: 24. Oktober 2026

Potassium Carbonate → HCID 89962883, Verbindung

https://huagongshe.com/de/reaction/337736

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPotassium CarbonateHCID 11430—
Edukt2,4-DifluoropyrimidineHCID 137716—
Edukt3-Fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclopentyl]oxy}benzenesulfonamideHCID 89963259—
LösungsmittelDimethylformamideHCID 6228—
ProduktHCID 89962883HCID 8996288363%

Reaktionsschritte

The reaction and aftertreatment were conducted in the same manner as in Example 16d by using 3-fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclopentyl]oxy}benzenesulfonamide (0.10 g, 0.29 mmol) prepared in Example 16c, 2,4-difluoropyrimidine (0.10 g, 0.88 mmol), potassium carbonate (0.16 g, 1.18 mmol) and DMF (3.0 mL), to yield the title compound (56 mg, 63%) as a colorless solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08889741B2
Quelldatensatzuspto-grants-2014_11
ORD IDord-33884d3794204d9ba3c577460bd50909
Quellennotizuspto-grants-2014_11