HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Aminotetralin, (R)- → HCID 86705881, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Aminotetralin, (R)- | HCID 7058072 | — |
| Edukt | N-Carbobenzyloxy-4-keto-L-proline | HCID 11076282 | — |
| Edukt | HCID 86705863 | HCID 86705863 | — |
| Produkt | HCID 86705881 | HCID 86705881 | 100% |
Reaktionsschritte
Following a procedure analogous to that for the synthesis of Compound D of Example 1, (S)-1-((benzyloxy)carbonyl)-4-oxopyrrolidine-2-carboxylic acid (Aldrich, 4.00 g, 15.2 mmol) and (R)-1,2,3,4-tetrahydronaphthalen-1-amine (Alfa Aesar, 2.23 mL, 15.2 mmol) were converted to the title compound (5.96 g, 100%). MS (ESI+) m/z 393.1 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08889712B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-b57b0c004422490bb033116c448e77a6 |
| Quellennotiz | uspto-grants-2014_11 |