HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(3R)-(+)-3-(Dimethylamino)pyrrolidine → HCID 178436921, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (3R)-(+)-3-(Dimethylamino)pyrrolidine | HCID 2758521 | — |
| Edukt | HCID 178436919 | HCID 178436919 | — |
| Produkt | HCID 178436921 | HCID 178436921 | 38,2% |
Reaktionsschritte
The title compound was prepared from (5-chloropyrazin-2-yl)(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (80 mg, 154 μmol) and (R)-3-dimethylaminopyrrolidine, (35 mg, 308 μmol) using the method of Example 32. The crude material was purified by HPLC Method C to afford (35 mg, 38%) of the title compound as white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08895544B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-55af3cd62afc4085b7a12114e78b59ad |
| Quellennotiz | uspto-grants-2014_11 |