Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 340039Erstellt: 23. Oktober 2026

(3R)-(+)-3-(Dimethylamino)pyrrolidine → HCID 178436921, Verbindung

https://huagongshe.com/de/reaction/340039

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(3R)-(+)-3-(Dimethylamino)pyrrolidineHCID 2758521—
EduktHCID 178436919HCID 178436919—
ProduktHCID 178436921HCID 17843692138,2%

Reaktionsschritte

The title compound was prepared from (5-chloropyrazin-2-yl)(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (80 mg, 154 μmol) and (R)-3-dimethylaminopyrrolidine, (35 mg, 308 μmol) using the method of Example 32. The crude material was purified by HPLC Method C to afford (35 mg, 38%) of the title compound as white solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08895544B2
Quelldatensatzuspto-grants-2014_11
ORD IDord-55af3cd62afc4085b7a12114e78b59ad
Quellennotizuspto-grants-2014_11