HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3,4-dihydro-2H-pyran → 2-[(3-Bromophenyl)methoxy]oxane
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| Edukt | Triphenylphosphonium bromide | HCID 80811 | — |
| Edukt | 3-Bromobenzyl alcohol | HCID 85141 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 2-[(3-Bromophenyl)methoxy]oxane | HCID 15282064 | — |
Reaktionsschritte
The alcohol of Step 1 (41.23 mmol), dihydropyran (12.5 mL, 137 mmol) and triphenylphosphine hydrobromide (725 mg, 2.11 mmol) were mixed together in 200 mL of CH2Cl2 and stirred for 2 days. The solvent was then evaporated and the title product was purified by flash chromatography on silica using EtOAc:toluene.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05856322 |
| Quelldatensatz | uspto-grants-1999_01 |
| ORD ID | ord-26550fcdd4ce4475a6345906644a73e3 |
| Quellennotiz | uspto-grants-1999_01 |