HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,2-Dibromoethane → 4-Hydroxypyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,2-Dibromoethane | HCID 7839 | — |
| Edukt | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| Edukt | 4-Hydroxypyrimidine | HCID 20695 | — |
| Produkt | 4-Hydroxypyrimidine | HCID 20695 | — |
| Produkt | 2-(1,6-Dihydro-6-oxopyrimidin-1-yl)ethyl chloride | HCID 19772555 | — |
Reaktionsschritte
When an equivalent amount of 4-pyrimidone is substituted for 1-ethoxycarbonyl-2H-indazolin-3-one and 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 19, 2-(1,6-dihydro-6-oxopyrimidin-1-yl)ethyl chloride is isolated after column chromatography (4-pyrimidone, Aldrich, 34%, B).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05053411 |
| Quelldatensatz | uspto-grants-1991_10 |
| ORD ID | ord-51b4306f523143c698d0cc229d69e0d4 |
| Quellennotiz | uspto-grants-1991_10 |