HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Benzyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione → 1-(4-Aminophenyl)-3-benzyl-3-azabicyclo[3.1.1]heptane-2,4-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Benzyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 14872633 | — |
| Edukt | Diethylether ethylacetate | HCID 21584169 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | 1-(4-Aminophenyl)-3-benzyl-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 14872638 | — |
Reaktionsschritte
In a manner analogous to that described in Example 1a, 2.46 g of 3-benzyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione are dissolved in 50 ml of ethyl acetate, hydrogenated in the presence of 0.3 g of 5% palladium-on-carbon and worked up. Melting point 164°-165.5° (from ether/ethyl acetate).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04764640 |
| Quelldatensatz | uspto-grants-1988_08 |
| ORD ID | ord-c9d1fe1a90394c208267d55bc38fcf9f |
| Quellennotiz | uspto-grants-1988_08 |