HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
cis-1-Acetyl-6-(4-benzyl-3,5-dimethylpiperazin-1-yl)-5-methoxyindoline → cis-6-(3,5-Dimethylpiperazin-1-yl)-5-methoxyindoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | cis-1-Acetyl-6-(4-benzyl-3,5-dimethylpiperazin-1-yl)-5-methoxyindoline | HCID 69835917 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Hydrochloric Acid | HCID 313 | — |
| Produkt | cis-6-(3,5-Dimethylpiperazin-1-yl)-5-methoxyindoline | HCID 11265480 | — |
Reaktionsschritte
The title compound was prepared from D4 by hydrogenation over 10% Pd/C using a similar procedure to Example 45 (98%), followed by hydrolysis in 2M HCl using a similar procedure to Description 3 (80%) to afford the product as a pale brown solid
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06747030B1 |
| Quelldatensatz | uspto-grants-2004_06 |
| ORD ID | ord-7364dfedd8244a10939e58d2c4a3bb0e |
| Quellennotiz | uspto-grants-2004_06 |