HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cyanamide → {4-Amino-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-hydroxy-phenyl)-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cyanamide | HCID 9864 | — |
| Edukt | 3-Hydroxyphenacyl bromide | HCID 6917206 | — |
| Edukt | 1-(4-Isothiocyanatophenyl)-4-cyclopropylmethylpiperazine | HCID 21958916 | — |
| Produkt | {4-Amino-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-hydroxy-phenyl)-methanone | HCID 21958956 | — |
Reaktionsschritte
This compound was prepared from cyanamide, 1-(4-isothiocyanatophenyl)-4-cyclopropylmethylpiperazine (of Example 1) and 2-bromo-1-(3-hydroxyphenyl)ethanone (of Example 14N) following the procedure used in Example 24. Mass spectrum (ES) MH+=410.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06756374B2 |
| Quelldatensatz | uspto-grants-2004_06 |
| ORD ID | ord-4cb40959e0924180b74493a2f7a25a37 |
| Quellennotiz | uspto-grants-2004_06 |