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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 357086Erstellt: 24. Oktober 2026

Hydrochloric Acid → 5-(1-Methylpiperazin-4-yl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione trihydrochloride

https://huagongshe.com/de/reaction/357086

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHydrochloric AcidHCID 313—
Edukt5-(1-Methylpiperazin-4-yl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dioneHCID 53897240—
LösungsmittelMethanolHCID 887—
Produkt5-(1-Methylpiperazin-4-yl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione trihydrochlorideHCID 86753345—

Reaktionsschritte

To a solution of 330 mg (0.76 mmol) of 5-(1-methylpiperazin-4-yl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 10 ml of methanol, concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 360 mg (82.0%, white crystal) of the desired product.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05840732
Quelldatensatzuspto-grants-1998_11
ORD IDord-fdbd4583c0464cda93b74123defe05c3
Quellennotizuspto-grants-1998_11