HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 5-(1-Methylpiperazin-4-yl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione trihydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | 5-(1-Methylpiperazin-4-yl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione | HCID 53897240 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 5-(1-Methylpiperazin-4-yl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione trihydrochloride | HCID 86753345 | — |
Reaktionsschritte
To a solution of 330 mg (0.76 mmol) of 5-(1-methylpiperazin-4-yl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 10 ml of methanol, concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 360 mg (82.0%, white crystal) of the desired product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05840732 |
| Quelldatensatz | uspto-grants-1998_11 |
| ORD ID | ord-fdbd4583c0464cda93b74123defe05c3 |
| Quellennotiz | uspto-grants-1998_11 |