HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Carbon tetrabromide → tert-Butyl 2-(2,2-dibromoethenyl)pyrrolidine-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Carbon tetrabromide | HCID 11205 | — |
| Edukt | Triphenylphosphine | HCID 11776 | — |
| Edukt | tert-butyl (2S)-2-formylpyrrolidine-1-carboxylate | HCID 2734674 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | tert-Butyl 2-(2,2-dibromoethenyl)pyrrolidine-1-carboxylate | HCID 14730280 | 47,9% |
Reaktionsschritte
Following the procedure of Example 3, 6.8 g of (S)-2-formyl-1-pyrrolidinecarboxylic acid, 1,1-dimethylethyl ester in 20 ml of methylene chloride is reacted with 40 g of triphenylphosphine, 26 g of carbon tetrabromide in 700 ml of methylene chloride to give 5.8 g of the desired product as a colorless solid, mp 58°-59° C., [α]D26° =+24°±1 (C=1.048%, methylene chloride).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05001142 |
| Quelldatensatz | uspto-grants-1991_03 |
| ORD ID | ord-b67f8ac7f60d4737b2e9d3e9ec551415 |
| Quellennotiz | uspto-grants-1991_03 |