Iodine → 2-Benzyl-6-phenyl-isothiazolo[5,4-d]pyrimidin-3-one

Beteiligte Stoffe

Reaktionsschritte

Using the procedure of Example 20, 2.0 g (6.22 mmol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid benzylamide (from Preparation 42) was reacted with 1.74 g (6.8 mmol) of iodine to give 1.74 g of the title compound after crystallization from isopropanol, mp 166-167° C.

Herkunft & Nachweise