Isopropyl N-cyano-4-pyridinecarboximidate → N-cyano-N'-(3-benzyloxybenzyl)-4-pyridinecarboximidamide

Beteiligte Stoffe

Reaktionsschritte

Isopropyl N-cyano-4-pyridinecarboximidate (0.30 g, 1.6 mmol) was dissolved in methanol (10 ml), and 3-benzyloxybenzylamine (0.42 g, 2.0 mmol) was added. The mixture was stirred at room temperature for 2 hours. After the reaction was completed, the reaction solution was then concentrated under reduced pressure. The residual concentrate was crystallized from methanol-diethyl ether to give the title compound (0.26 g, 0.8 mmol, yield: 48%) as colorless crystals.

Herkunft & Nachweise