HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Water → 3-(1H-Indol-7-YL)propanenitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Water | HCID 962 | — |
| Edukt | Piperidine | HCID 8082 | — |
| Edukt | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Edukt | Benzoic acid, 3-methyl-2-nitro-, methyl ester | HCID 79621 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 3-(1H-Indol-7-YL)propanenitrile | HCID 19959105 | — |
Reaktionsschritte
A solution of methyl 3-methyl-2-nitrobenzoate (43 g, 0.22 mole), dimethylformamide dimethyl acetal (52.5 g, 0.44 mole) and piperidine (18.7 g, 0.22 mole) in dimethylformamide (120 ml) is heated under reflux for 24 hours, cooled and poured into water to give the crude product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05486612 |
| Quelldatensatz | uspto-grants-1996_01 |
| ORD ID | ord-99b69e106a784f89aab343a351df0e89 |
| Quellennotiz | uspto-grants-1996_01 |