Phenyl isocyanate → 1-Phenyl-4-cyano-5-(phenylureido)-pyrazole

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

9.0 g (80 mmol) of potassium tert-butylate and 8.7 ml (80 mmol) of phenyl isocyanate were added to a solution of 5.52 g (30 mmol) of 1-phenyl-4-cyano-5-aminopyrazole in 100 ml of toluene. The mixture was heated for 15 hours at 80° C. and then cooled, the insoluble constituents were separated off and the resulting solution was acidified with acetic acid, the product crystallizing out. Yield: 96%.

Herkunft & Nachweise