HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Nipecotic Acid → 1-((Benzyloxy)carbonyl)piperidine-3-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Nipecotic Acid | HCID 4498 | — |
| Edukt | Benzyl chloroformate | HCID 10387 | — |
| Produkt | 1-((Benzyloxy)carbonyl)piperidine-3-carboxylic acid | HCID 234339 | — |
Reaktionsschritte
By substantially following the procedures of Example 1,A, 25.0 g (194 mmol) of nipecotic acid was protected with benzylchloroformate under basic conditions to afford 18.0 g (68 mmol; 35%) of analytically pure N-Cbz-nipecotic acid as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05488037 |
| Quelldatensatz | uspto-grants-1996_01 |
| ORD ID | ord-ef87f616f49c4ab4b0a9b1b7e0b2a433 |
| Quellennotiz | uspto-grants-1996_01 |