HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethylformamide → 8-(4-Benzyloxy-phenyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid isopropyl-(2-methoxy-ethyl)-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethylformamide | HCID 6228 | — |
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | N-(2-Methoxyethyl)isopropylamine | HCID 551575 | — |
| Edukt | 8-[p-(benzyloxy)phenyl]-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid | HCID 19353629 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Lösungsmittel | 1,4-Dioxane | HCID 31275 | — |
| Produkt | 8-(4-Benzyloxy-phenyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid isopropyl-(2-methoxy-ethyl)-amide | HCID 56629768 | — |
Reaktionsschritte
From 8-[p-(benzyloxy)phenyl]-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid with SOCl2 and DMF in toluene. Then treatment with triethylamine and isopropyl-(2-methoxy-ethyl)-amine in dioxan.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06030984 |
| Quelldatensatz | uspto-grants-2000_02 |
| ORD ID | ord-11e1f58d569448248917e951548596ef |
| Quellennotiz | uspto-grants-2000_02 |