HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 4-{[6-({3-(Aminocarbonyl)-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-thienyl}amino)pyridin-2-yl]methyl}morpholine-3-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide | HCID 58216638 | — |
| Edukt | 4-[(6-Bromopyridin-2-yl)methyl]morpholine-3-carboxamide | HCID 59525573 | — |
| Produkt | 4-{[6-({3-(Aminocarbonyl)-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-thienyl}amino)pyridin-2-yl]methyl}morpholine-3-carboxamide | HCID 59526025 | — |
Reaktionsschritte
The title compound was prepared as described in Example 1 using 2-amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (80 mg, 0.27 mmol) and 4-[(6-bromopyridin-2-yl)methyl]morpholine-3-carboxamide (82 mg, 0.27 mmol) as starting materials.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08367706B2 |
| Quelldatensatz | uspto-grants-2013_02 |
| ORD ID | ord-08b0f3d29a1a46f0b2ffbd5936399831 |
| Quellennotiz | uspto-grants-2013_02 |