HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
O-(Tetrahydropyran-2-yl)hydroxylamine → 3-[(2-fluoro-4-iodophenyl)amino]-N-(tetrahydro-2H-pyran-2-yloxy)isonicotin-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | O-(Tetrahydropyran-2-yl)hydroxylamine | HCID 5142091 | — |
| Edukt | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| Produkt | 3-[(2-fluoro-4-iodophenyl)amino]-N-(tetrahydro-2H-pyran-2-yloxy)isonicotin-amide | HCID 11691076 | — |
Reaktionsschritte
3-[(2-fluoro-4-iodophenyl)amino]-N-(tetrahydro-2H-pyran-2-yloxy)isonicotin-amide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.4 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.52 mmol of O-(tetrahydro-pyran-2-yl)-hydroxylamine. LC/MS [9.07 min; 458 (M+1)]
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08524911B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-a0c0207bf5304ba58007c7f7ed81adad |
| Quellennotiz | uspto-grants-2013_09 |