HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4,6-Dichloro-2-methyl-5-nitropyrimidine → 4,6-Dichloro-2-methylpyrimidin-5-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4,6-Dichloro-2-methyl-5-nitropyrimidine | HCID 83192 | — |
| Katalysator | Nickel | HCID 935 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | 4,6-Dichloro-2-methylpyrimidin-5-amine | HCID 736674 | — |
Reaktionsschritte
The third intermediate, 4,6-dichloro-2-methyl-5-nitropyrimidine is hydrogenated over Raney-Ni as a 10% to 30% solution in toluene to afford the corresponding compound, 4,6-dichloro-2-methyl-5-aminopyrimidine, as a fourth intermediate.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05816260 |
| Quelldatensatz | uspto-grants-1998_10 |
| ORD ID | ord-b8efa4f6156f4b12be49de0edf7b530d |
| Quellennotiz | uspto-grants-1998_10 |