4-Chloro-6,7-dimethoxyquinazoline hydrochloride → 4-(3-Chloro-4-phenylthioanilino)-6,7-dimethoxyquinazoline hydrochloride salt

Beteiligte Stoffe

Reaktionsschritte

Using an analogous procedure to that described in Example 1 except that the reaction mixture was heated to reflux for 16 hours, 4-amino-2-chlorophenyl phenyl sulphide was reacted with 4-chloro-6,7-dimethoxyquinazoline hydrochloride to give 4-(3-chloro-4-phenylthioanilino)-6,7-dimethoxyquinazoline hydrochloride salt in 71% yield, m.p. 245°-247° C.;

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