HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Chloroquinazolin-6-yl acetate → 6-Acetoxy-4-[3-methyl-4-(2-pyridylmethoxy)anilino]quinazoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Chloroquinazolin-6-yl acetate | HCID 18967624 | — |
| Edukt | 3-Methyl-4-(pyridin-2-ylmethoxy)aniline | HCID 23438288 | — |
| Produkt | 6-Acetoxy-4-[3-methyl-4-(2-pyridylmethoxy)anilino]quinazoline | HCID 18967611 | 35% |
Reaktionsschritte
Using an analogous procedure to that described in Example 1, 6-acetoxy-4-chloroquinazoline was reacted with 5-amino-2-tolyl 2-pyridylmethyl ether to give 6-acetoxy-4-[3-methyl-4-(2-pyridylmethoxy)anilino]quinazoline in 35% yield, m.p. 149°-151° C.;
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05821246 |
| Quelldatensatz | uspto-grants-1998_10 |
| ORD ID | ord-2da5c69a5636427698c7bb8d64aa4f81 |
| Quellennotiz | uspto-grants-1998_10 |