HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrogen Bromide → N-((5-Fluoropyridin-3-yl)methyl)-6-hydroxy-2-isopropyl-1-(pyridin-3-ylmethyl)-1H-indole-3-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrogen Bromide | HCID 260 | — |
| Edukt | 3-(Bromomethyl)pyridine | HCID 245934 | — |
| Edukt | (5-Fluoropyridin-3-yl)methanamine | HCID 45116207 | — |
| Edukt | 2-isopropyl-6-methoxy-1H-indole-3-carbaldehyde | HCID 59762309 | — |
| Produkt | N-((5-Fluoropyridin-3-yl)methyl)-6-hydroxy-2-isopropyl-1-(pyridin-3-ylmethyl)-1H-indole-3-carboxamide | HCID 59762408 | — |
Reaktionsschritte
The title compound was prepared from 2-isopropyl-6-methoxy-1H-indole-3-carbaldehyde (Compound 137), 3-(bromomethyl)pyridine.HBr, and (5-fluoropyridin-3-yl)methanamine (Compound 145) by, in order, General Procedure J, General Procedure K, General Procedure C, and General Procedure L.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08524917B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-164e0292d7c940bb90896a1cf1027007 |
| Quellennotiz | uspto-grants-2013_09 |