HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3,4-Difluorophenyl isocyanate → (S)-Methyl 2-(6-(4-(3-(3,4-difluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3,4-Difluorophenyl isocyanate | HCID 2734708 | — |
| Edukt | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| Produkt | (S)-Methyl 2-(6-(4-(3-(3,4-difluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123749611 | — |
Reaktionsschritte
The compound of example 31 was prepared analogous to compound of example 7 by reaction of compound of example 6 with 3,4-difluorophenyl isocyanate. The compound of example 31 was used directly without isolation for the preparation of compound of example 32.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08748426B2 |
| Quelldatensatz | uspto-grants-2014_06 |
| ORD ID | ord-e08fb303080b4addbdc3b870c17eaeb2 |
| Quellennotiz | uspto-grants-2014_06 |