4-Fluorophenyl isothiocyanate → (S)-Methyl 2-(5-(4-(3-(3-fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate

Beteiligte Stoffe

Reaktionsschritte

The compound of example 276 was prepared analogous to compound of example 256 by reaction of compound of example 223 with 4-fluorophenyl isothiocyanate. The compound of example 276 was used directly without isolation, for the preparation of compound of example 277.

Herkunft & Nachweise