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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 403903Erstellt: 24. Oktober 2026

3-Methoxyphenyl isothiocyanate → (S)-Methyl 2-(5-(4-(3-(3-methoxyphenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate

https://huagongshe.com/de/reaction/403903

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-Methoxyphenyl isothiocyanateHCID 137832—
Edukt(S)-Methyl 2-(5-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731499—
Edukt(S)-Methyl 2-(5-(4-(3-(2-fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731509—
Produkt(S)-Methyl 2-(5-(4-(3-(3-methoxyphenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 123917782—

Reaktionsschritte

The compound of example 278 was prepared analogous to compound of example 256 by reaction of compound of example 223 with 3-methoxyphenyl isothiocyanate. The compound of example 278 was used directly without isolation, for the preparation of compound of example 279.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08748426B2
Quelldatensatzuspto-grants-2014_06
ORD IDord-d8e80cef67594a5ebd2a3e712e4d7df9
Quellennotizuspto-grants-2014_06