Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Formamide | HCID 713 | — |
| Edukt | 4-Aminobenzene-1,3-dioic acid | HCID 11355852 | — |
| Lösungsmittel | Acetone | HCID 180 | — |
| Produkt | 4-Oxo-3,4-dihydroquinazoline-6-carboxylic acid | HCID 135703881 | 61% |
Reaktionsschritte
A mixture of 4-amino isophthalic acid (17 g, 0.093 mol) and formamide (85 mL) was heated at 180° C. for 5 h. The reaction mixture was cooled to RT and added acetone. The solid precipitate thus obtained was stirred for 2 h, filtered and dried to give 4-oxo-3,4-dihydroquinazoline-6-carboxylic acid (11 g, 61%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US08106214B2 |
|---|
| Quelldatensatz | uspto-grants-2012_01 |
|---|
| ORD ID | ord-298110cfea3646b4a00a3691ade77287 |
|---|
| Quellennotiz | uspto-grants-2012_01 |
|---|
