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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 425985Erstellt: 24. Oktober 2026

Pyridine → HCID 66703605, Verbindung

https://huagongshe.com/de/reaction/425985

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPyridineHCID 1049—
Edukt2-Fluoro-4-(trifluoromethyl)benzoyl chlorideHCID 145580—
Edukt7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-oneHCID 33699394—
LösungsmittelWaterHCID 962—
ProduktHCID 66703605HCID 66703605—

Reaktionsschritte

2-Fluoro-4-(trifluoromethyl)benzoyl chloride was added to a pyridine solution of 7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-one, followed by stirring at room temperature for 12 hours. Water was added to the reaction liquid, followed by stirring for 30 minutes and then the precipitated crystals were collected by filtration to obtain 2-fluoro-N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-4-(trifluoromethyl)benzamide.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08106190B2
Quelldatensatzuspto-grants-2012_01
ORD IDord-37e90418f05547b9ae14e3e6437759f8
Quellennotizuspto-grants-2012_01