HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyridine → HCID 66703605, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyridine | HCID 1049 | — |
| Edukt | 2-Fluoro-4-(trifluoromethyl)benzoyl chloride | HCID 145580 | — |
| Edukt | 7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-one | HCID 33699394 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | HCID 66703605 | HCID 66703605 | — |
Reaktionsschritte
2-Fluoro-4-(trifluoromethyl)benzoyl chloride was added to a pyridine solution of 7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-one, followed by stirring at room temperature for 12 hours. Water was added to the reaction liquid, followed by stirring for 30 minutes and then the precipitated crystals were collected by filtration to obtain 2-fluoro-N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-4-(trifluoromethyl)benzamide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08106190B2 |
| Quelldatensatz | uspto-grants-2012_01 |
| ORD ID | ord-37e90418f05547b9ae14e3e6437759f8 |
| Quellennotiz | uspto-grants-2012_01 |