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HRID 42696Erstellt: 24. Oktober 2026

6-Chloro-5-formyl-1,3-dimethyluracil → 1,3-Dimethyl-6-(methylthio)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde

https://huagongshe.com/de/reaction/42696

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt6-Chloro-5-formyl-1,3-dimethyluracilHCID 319971—
EduktSodium methanethiolateHCID 4378561—
Produkt1,3-Dimethyl-6-(methylthio)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehydeHCID 86658685—

Reaktionsschritte

The process described in Method D was followed. 6-Chloro-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde (0.404 g, 2.00 mmol) and sodium thiomethoxide (0.154 g, 2.20 mmol in 4 ml 1,4-dioxane) were used to obtain the title compound. The crude product was purified by washing with n-pentane.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08536210B2
Quelldatensatzuspto-grants-2013_09
ORD IDord-c7198cb84a3645cf8fbf9974ac7f14d0
Quellennotizuspto-grants-2013_09