p-Toluenesulfonic acid → 1-Pyrrolidino-1-cyclohexene

Beteiligte Stoffe

Reaktionsschritte

1 g of para-toluenesulphonic acid is added to a mixture of 20 mmol of cyclohexanone and 22 mmol of pyrrolidine in 200 ml of dry benzene. The reaction mixture is stirred at reflux until, in the infra-red, the ketone has disappeared, with the enamine concomitantly appearing. The solvent is then evaporated off and the crude residue is purified by distillation in vacuo.

Herkunft & Nachweise