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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 43080Erstellt: 24. Oktober 2026

6-(4-Methylpiperazin-1-yl)pyridin-3-amine → 8-Naphthalen-1-yl-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]amide

https://huagongshe.com/de/reaction/43080

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt6-(4-Methylpiperazin-1-yl)pyridin-3-amineHCID 2763390—
Edukt8-Naphthalen-1-yl-quinoxaline-5-carboxylic acid [4-(4-methyl-piperazin-1-yl)phenyl]-amideHCID 44515355—
Produkt8-Naphthalen-1-yl-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]amideHCID 59292934—

Reaktionsschritte

The title compound was prepared in analogy to the procedure described in Step 14.1 but stirring the reaction mixture for 20 h at it and using 6-(4-methylpiperazin-1-yl)-pyridin-3-ylamine (prepared as described in Example 33 but using N-methyl-piperazine in Step 33.2) and 8-naphthalen-1-yl-quinoxaline-5-carboxylic acid (Example 46). Title compound: ESI-MS: 475.0 [M+H]+; tR=3.76 min (System 1).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08536175B2
Quelldatensatzuspto-grants-2013_09
ORD IDord-2f03f2f53ea845e79c20cecc01c56688
Quellennotizuspto-grants-2013_09