HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-bromobutanimide → 2-Bromo-5-methoxybenzyl bromide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-bromobutanimide | HCID 67184 | — |
| Edukt | 1-Bromo-4-methoxy-2-methylbenzene | HCID 117915 | — |
| Katalysator | Azobisisobutyronitrile | HCID 6547 | — |
| Lösungsmittel | 1,1-Dichloroethane | HCID 6365 | — |
| Produkt | 2-Bromo-5-methoxybenzyl bromide | HCID 3525951 | 64% |
Reaktionsschritte
To a solution of 2-bromo-5-methoxytoluene (50 g, 0.25 mol) in dichloroethane (375 ml), N-bromosuccinimide (48.8 g, 0.275 mol) and AIBN (1.36 g) were added and the reaction was refluxed for 4 h. The cooled solution was filtered and the solvent was evaporated to give a weight of 44.8 g crude 1-Bromo-2-bromomethyl-4-methoxy-benzene (64% yield).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06323345B1 |
| Quelldatensatz | uspto-grants-2001_11 |
| ORD ID | ord-07f7a5122f7f4d769565c3dbd6b6dab5 |
| Quellennotiz | uspto-grants-2001_11 |