HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Citric Acid → Formoterol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Citric Acid | HCID 311 | — |
| Edukt | Sodium Chloride | HCID 5234 | — |
| Edukt | Trisodium citrate | HCID 6224 | — |
| Edukt | HCID 11954385 | HCID 11954385 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Formoterol | HCID 3410 | — |
Reaktionsschritte
To a 5 L stainless steel vessel were added 0.68 g citric acid USP, 1.99 g sodium citrate USP, and 17.5 g sodium chloride USP. Purified water USP (2 L) was added to the stainless steel vessel and the contents were mixed with an overhead stirrer at a speed of 240 rpm for 10 minutes. Formoterol fumarate dihydrate (0.17 g for low dosage strength formulation, 0.34 g for high dosage strength formulation) was added and the solution was stirred at 240 rpm for 90 minutes.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06667344B2 |
| Quelldatensatz | uspto-grants-2003_12 |
| ORD ID | ord-6317a0f1cf7b47ee8cb8e7e5955d3cb5 |
| Quellennotiz | uspto-grants-2003_12 |