HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3,4-Dimethoxyphenethyl alcohol → Methyl 2-Hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-diphenylpropionate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3,4-Dimethoxyphenethyl alcohol | HCID 81911 | — |
| Edukt | Methyl 3,3-diphenyloxirane-2-carboxylate | HCID 10587027 | — |
| Katalysator | Boron trifluoride etherate | HCID 8000 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | Methyl 2-Hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-diphenylpropionate | HCID 18756198 | — |
Reaktionsschritte
7 g (27.5 mmol) of methyl 3,3-diphenyl-2,3-epoxypropionate and 5.5 g (30.2 mmol) of 2-(3,4-dimethoxyphenyl)ethanol were dissolved in 20 ml of dichloromethane and, at room temperature, 5 drops of boron trifluoride etherate were added. The solution was stirred for 2 hours. The solvent was then distilled off, and the residue (10.7 g, 89%) was immediately reacted further.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06670367B1 |
| Quelldatensatz | uspto-grants-2003_12 |
| ORD ID | ord-25a8cc06e044439baf8afa2a89b389b2 |
| Quellennotiz | uspto-grants-2003_12 |