2-Methyl-3-methylthio-4-morpholino-5-fluoro-7-bromoindole → 2-Methyl-4-morpholino-5-fluoro-7-bromoindole

Beteiligte Stoffe

Reaktionsschritte

Raney nickel (400 g) was added to a solution of 58 g of 2-methyl-3-methylthio-4-morpholino-5-fluoro-7-bromoindole in 1 l of dioxane and the mixture was allowed to react at room temperature for 4 hours. After completion of the reaction Raney nickel was removed by filtration, and the filtrate was concentrated under reduced pressure. 33 g of 2-methyl-4-morpholino-5-fluoro-7-bromoindole was obtained.

Herkunft & Nachweise