N-ethyl-3-methylaniline → N-Ethyl-3-Hydroxy-7-Methyl-1,2,3,4-Tetrahydroquinoline

Beteiligte Stoffe

Reaktionsschritte

N-ethyl-m-toluidine (1.0 mole) and epichlorohydrin (225 g) were mixed and allowed to stand three days at room temperature. The reaction mixture was heated at 140°-145° C. for 6 hrs. and then distilled under vacuum. The product (100 g) which boiled at 143° C. at 1.1 mmHg was recovered in 52% of the theoretical yield.

Herkunft & Nachweise