HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → Benzyl 4-((tert-butoxycarbonyl)amino)piperidine-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Benzyl chloroformate | HCID 10387 | — |
| Edukt | 4-(N-Boc-amino)piperidine | HCID 723833 | — |
| Produkt | Benzyl 4-((tert-butoxycarbonyl)amino)piperidine-1-carboxylate | HCID 21981786 | 81,1% |
Reaktionsschritte
The same operation as in Example (227a) was performed using 4-[(tert-butoxycarbonyl)amino]piperidine (2.00 g, 9.99 mmol), benzyl chloroformate (2.14 mL, 15.0 mmol) and triethylamine (3.48 mL, 25.0 mmol), to obtain 2.71 g of the title compound as a white solid (81%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08536197B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-62ef6d9df10048689be273132c9cefaf |
| Quellennotiz | uspto-grants-2013_09 |