Mannitol → Docetaxel Mannitol

Beteiligte Stoffe

Reaktionsschritte

Lyophilization is performed to yield vials containing lyophilized cake comprising docetaxel and mannitol in a ratio of 1:1.5 to 1:3, preferably 1:1.8 to 1:2.7, more preferably 1:2.0 to 1:2.5, and most preferably 1:2.2. The amount of cake may vary, for example a 1:2.2 ratio may be obtained by a vial comprising 20 mg docetaxel and 44 mg mannitol, a vial comprising 80 mg docetaxel and 176 mg mannitol, or a vial comprising 120 mg docetaxel and 264 mg mannitol.

Herkunft & Nachweise