HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Phenyl-2-pyridone → Z-Val-Val-OMe
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-Phenyl-2-pyridone | HCID 87889 | — |
| Edukt | Sodium | HCID 5360545 | — |
| Edukt | 6-Hydroxynicotinonitrile | HCID 7062197 | — |
| Edukt | HCID 178493244 | HCID 178493244 | — |
| Edukt | 6-(2-Phenylethyl)pyridin-2(1h)-one | HCID 178516001 | — |
| Edukt | HCID 178516071 | HCID 178516071 | — |
| Edukt | HCID 178517620 | HCID 178517620 | — |
| Produkt | Z-Val-Val-OMe | HCID 12286262 | — |
Reaktionsschritte
When a sodium salt of 6-n-amyl-2-hydroxypyridine, 5-cyano-2-hydroxypyridine, 2-hydroxy-4-methoxypyridine, 2-hydroxy-6-phenylpyridine, 2-hydroxy-6-phenethylpyridine or 1-hydroxyisoquinoline is used in place of the sodium salt of 2-hydroxypyridine, the yields of benzyloxycarbonyl-L-valyl-L-valine methyl ester are 72, 83, 81, 76, 80 and 73 percent, respectively.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | USRE029369 |
| Quelldatensatz | uspto-grants-1977_08 |
| ORD ID | ord-8bd821eceeac4e6bb644a6d057221ae8 |
| Quellennotiz | uspto-grants-1977_08 |