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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 443600Erstellt: 24. Oktober 2026

2,6-Dimethylaniline → Methyl N-(2,6-dimethylphenyl)-DL-alaninate

https://huagongshe.com/de/reaction/443600

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2,6-DimethylanilineHCID 6896—
EduktMethyl 2-bromopropionateHCID 95576—
EduktSodium BicarbonateHCID 516892—
ProduktMethyl N-(2,6-dimethylphenyl)-DL-alaninateHCID 9455579,6%

Reaktionsschritte

Furthermore, the reaction of 2,6-dimethylaniline at 120°-125° C., in the presence of sodium bicarbonate as an acid-binding agent, with a three-fold molar excess of methyl 2-bromopropionate has been disclosed in U.S. Pat. No. 4,008,066. With this process, N-(1'-methoxycarbonylethyl)-2,6-dimethylaniline is obtained in a yield of 79.6% of theory.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04260782
Quelldatensatzuspto-grants-1981_04
ORD IDord-6f962d8509e74197826dff60cf811abf
Quellennotizuspto-grants-1981_04