HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → (1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | tert-butoxycarbonyl-(1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine | HCID 57444165 | — |
| Lösungsmittel | 1,4-Dioxane | HCID 31275 | — |
| Produkt | (1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine hydrochloride | HCID 57444166 | — |
Reaktionsschritte
A solution of 630 mg (1.884 mmol) of N-(tert-butoxycarbonyl)-(1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine in 20 mL of dioxane was treated with 2.5 mL of HCl 4N in dioxane overnight. The solvent was removed under vacuo and the solid was triturated with diethylether yielding 560 mg of the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08541429B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-015e1834be00428fb7598a2baa2a1816 |
| Quellennotiz | uspto-grants-2013_09 |