HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanol → ethyl (2R)-5-oxopyrrolidine-2-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanol | HCID 702 | — |
| Edukt | D-Pyroglutamic acid | HCID 439685 | — |
| Lösungsmittel | Sulfuric Acid | HCID 1118 | — |
| Produkt | ethyl (2R)-5-oxopyrrolidine-2-carboxylate | HCID 643508 | — |
Reaktionsschritte
To a solution of D-pyroglutamic acid (compound I-A, 20.4 g, 0.16 mol) in 100 mL of EtOH, 1.2 mL of conc. sulfuric acid was added. The mixture was heated under reflux overnight. Solvent was removed under reduced pressure to give (R)-ethyl 5-oxopyrrolidine-2-carboxylate (compound II-AA).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08541418B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-a7bce6362165468fa455f7ec24641f1b |
| Quellennotiz | uspto-grants-2013_09 |