HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzofuran-2-carboxylic acid → 1-[(2-Benzofuranylcarbonyl)amino]cyclohexanecarboxylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzofuran-2-carboxylic acid | HCID 10331 | — |
| Edukt | Ethyl 1-aminocyclohexane-1-carboxylate hydrochloride | HCID 11241228 | — |
| Produkt | 1-[(2-Benzofuranylcarbonyl)amino]cyclohexanecarboxylic acid ethyl ester | HCID 57672902 | 80,3% |
Reaktionsschritte
3.11 g (15 mmol) of 1-aminocyclohexanecarboxylic acid ethyl ester hydrochloride was used instead of 1-aminocyclohexanecarboxylic acid methyl ester hydrochloride, and 2.43 g (15 mmol) of benzofuran-2-carboxylic acid was used instead of 3-furancarboxylic acid in the process according to Reference Example 15 to obtain 3.80 g (80%) of the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08481725B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-64eded0a67d5420d85f2d3e711cc863f |
| Quellennotiz | uspto-grants-2013_07 |