Ammonia → Quinoline-6-carboxamide

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To a solution of methyl quinoline-6-carboxylate (148 g, 0.79 mol) in methanol (600 ml.), aqueous ammonia (800 ml) was added and then stirred at 45° C. for 12 h. The reaction mixture was concentrated to afford the title compound as a dark red solid (120 g, 88%).

Herkunft & Nachweise