HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetoxyacetyl chloride → 2-Oxo-2-[2-[[3-[3-(trifluoromethoxy)phenyl]-1-benzofuran-5-yl]carbonyl]hydrazino]ethyl acetate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetoxyacetyl chloride | HCID 26297 | — |
| Edukt | 3-[3-(Trifluoromethoxy)phenyl]-1-benzofuran-5-carbohydrazide | HCID 68664388 | — |
| Produkt | 2-Oxo-2-[2-[[3-[3-(trifluoromethoxy)phenyl]-1-benzofuran-5-yl]carbonyl]hydrazino]ethyl acetate | HCID 68663979 | 94% |
Reaktionsschritte
In the same manner as in Reference Example 61 and using 3-[3-(trifluoromethoxy)phenyl]-1-benzofuran-5-carbohydrazide instead of ethyl 2-aminoisonicotinate and acetoxyacetyl chloride instead of 3-phenylpropanoyl chloride, the title compound (yield 94%) was obtained as colorless crystals.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08492378B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-b8ee4722838a4af8a11e55105d686a9e |
| Quellennotiz | uspto-grants-2013_07 |