HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(Chloromethyl)benzoic acid → 3-[[[5-[1-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-1,3,4-oxadiazol-2-yl]thio]methyl]benzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(Chloromethyl)benzoic acid | HCID 241752 | — |
| Edukt | HCID 178492021 | HCID 178492021 | — |
| Produkt | 3-[[[5-[1-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-1,3,4-oxadiazol-2-yl]thio]methyl]benzoic acid | HCID 68663958 | 31% |
Reaktionsschritte
In the same manner as in Example 1 and using 5-[1-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-1,3,4-oxadiazole-2-thiol instead of 5-(benzothiazol-6-yl)-1,3,4-oxadiazole-2-thiol and 3-(chloromethyl)benzoic acid instead of 3-(trifluoromethyl)benzyl chloride, the title compound (yield 31%) was obtained as colorless crystals.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08492378B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-56b7ed740aea43c38af46bdc134eb460 |
| Quellennotiz | uspto-grants-2013_07 |