Sodium methanolate methanol → 2-(2-Methoxypyrimidine-4-yl)-6-(3-fluoropropoxy)benzothiophene

Beteiligte Stoffe

Reaktionsschritte

2-(2-Methoxypyrimidine-4-yl)-6-(3-fluoropropoxy)benzothiophene (1-37, 75 mg, 99%) was prepared in the same manner as in Example 34 as a yellow solid using 2-(2-chloropyrimidine-4-yl)-6-(3-fluoropropoxy)benzothiophene (105c, 70 mg, 0.22 mmol) obtained in Preparation Example 21 and a 0.5 M sodium methoxide methanol solution (0.66 mL, 0.33 mmol).

Herkunft & Nachweise