3-Methyluracil → 1-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-3-methylpyrimidine-2,4(1H,3H)-dione

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Reaktionsschritte

The title compound was prepared according to Method B and the experimentals described for compound 92 from 3-(chloromethyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine hydrochloride and 3-methylpyrimidine-2,4(1H,3H)-dione. M/e+ 367 for C19H16ClN4O2 (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.22 (d, J=5.8 Hz, 1H), 7.66 (d, J=8.4 Hz, 2H), 7.45 (d, J=8.4 Hz, 2H), 7.30 (m, 1H), 6.91 (t, J=6.6 Hz, 1H), 6.63 (d, J=8.0 Hz, 1H), 5.56 (d, J=8.0 Hz, 1H), 5.45 (s, 2H), 5.26 (d, J=0.7 Hz, 1H), 3.34 (s, 3H) ppm.

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