HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Guaiacol → 2-Methoxy-3-{3-[3-(2-methoxy-phenoxy)-propoxy]-phenyl}-propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Guaiacol | HCID 460 | — |
| Edukt | 3-[3-(3-Bromo-propoxy)-phenyl]-2-methoxy-propionic acid methyl ester | HCID 58822861 | — |
| Edukt | (2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acid | HCID 58822897 | — |
| Produkt | 2-Methoxy-3-{3-[3-(2-methoxy-phenoxy)-propoxy]-phenyl}-propionic acid | HCID 18443261 | — |
Reaktionsschritte
The title compound was prepared from 3-[3-(3-bromo-propoxy)-phenyl]-2-methoxy-propionic acid methyl ester (Example 323, Step 1) and 2-methoxyphenol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1). The enatiomers were separated by chiral HPLC. MS (ES) for C20H24O6 [M+Na]+: 383.4.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07192982B2 |
| Quelldatensatz | uspto-grants-2007_03 |
| ORD ID | ord-ac4e413df6394a17a4382d286819533b |
| Quellennotiz | uspto-grants-2007_03 |